Are there people still having this problem?
We're running a Windows 7 x64 Lab environment, running Cadence SPB 16.5. We have similar issues, with various DLL files not being found after a system reboot. The above response about opening the PATH variable for editing, changing nothing and selecting OK seems to work for us (also the install config utility seems to fix this too), but only until the system is yet again rebooted.
Has anyone recieved any insight from Cadence about this?