I recommend filing a Service Request via sourcelink.cadence.com and sending in your spectre.out and CDS.log files. Is Spectre failing? Or is the error occuring when you are reading in/plotting the data? Are you running 32 bit or 64 bit spectre?
If the simulation data is from Spectre and the waveform tool used is WaveScan, and simulation results directory is greated than 2G in size, then please follow solution# 11264780
split your PSF directory in 2 Gigs chunks when you run big simulations next time.
Staff Support AE, Global Customer Support
Cadence Design Systems, Inc.